ISSN: 1305-3876
Hakkında: Özel sayılar şeklinde yayınlanır.
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Benign Prostate Hyperplasia: Epidemiology And Natural History
Dr. Murat LEKİLİ,a Dr. Talha MÜEZZİNOĞLUa
a Üroloji AD, Celal Bayar Üniversitesi Tıp Fakültesi, MANİSA
Benign prostate hyperplasia (BPH) is the most prevalent disease in older men whose quality of life including daily activity and uninterrupted sleeping is highly affected with lower urinary tract symptoms. The incidence of histopathological BPH and the prevalence of lower urinary tract symptoms (LUTS) increase with aging. Severe or mild symptomatology are observed in half of the men who diagnosed histologically.
BPH are defined as histologically stromal and epithelial cell hyperplasia beginning in periurethral zone of prostate. But, there is still no consensus on definition of clinical disease. Therefore, prevalence of the disease differs due to the different definitions in researches. Epidemiological researches in our country showed that the incidence of LUTS in men older than forty was 80-85%. It is reported that the most prevalent symptoms were consequently nocturia, frequency and decreased urinary flow; in contrast hesitancy was the lowest observed symptom.
The relation between BPH and LUTS is relatively complex, because the patient with LUTS does not necessarily have enlarged prostate and similarly, enlarged prostate does not cause LUTS in every case.
The natural history of BPH should be known properly in order to understand complications and the effectiveness of therapeutic procedures. Therefore, multicenter trials must be done for obtaining data of BPH in our country.Keywords: Benign prostate hyperplasia, epidemiology, natural history, lower urinary tract symptomTurkiye Klinikleri J Surg Med Sci 2005, 1(1):15-23
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